منابع مشابه
Experimental leprosy with nude mice.
In 1960, Shepard10) reported a model of experimental leprosy of mouse by means of footpad inoculation technic. This experimental leprosy has been widely utilized in the field of leprosy research, but grwoth of Mycobacterium leprae in normal mouse foot-pad is limited and maximum harvest of M. leprae from infected normal mouse foot-pad is about 106. Several studies were reported concerning immuno...
متن کاملExperimental Q fever infection in congenitally athymic nude mice.
Congenitally athymic nude (nu/nu) mice and their phenotypically normal (nu/+) euthymic littermates were exposed to Coxiella burnetii administered as small-particle aerosols. After challenge, both strains of mice became infected, as characterized by rickettsemia, viable rickettsiae in the spleen, and serological conversion. The major difference noted was that euthymic animals had cleared rickett...
متن کاملExperimental human leprosy in the footpad of mice.
Multiplication of Mycobacteria leprae in the foot pads of mice has been reported by Shepard . 1 o The increase has been up to 1 ,000 fold. Other workers like Chatterji4 and BergeP have also reported successful transmission of M. leprae in ra ts and mice by using differen t s trains of animals and different food and technique. Mukherj i 6, 7 has not been able to confirm their works . This work ...
متن کاملThoracic duct lymphocytes in experimental lepromatous leprosy in mice.
Progress in leprosy research was very restricted until recently, for it was, and still is, impossible to grow the causative organism M ycohacterium leprae in vitro. The work of Shepard (Ii) , however, opened up new possibilities, for he demonstrated that M. leprae can be grown in the footpads of mice. Rces and Weddell (2,3) and colleagues have further contributed to experimental leprosy in mice...
متن کاملTumor in Nude Mice
Erythropoietin was measured by exhypoxic polycythemic mouse method in the course of a 64-yr-old male with renal cell carcinoma associated with erythrocytosis. Serum erythropoietin fluctuated with progression of the disease. Preoperative elevated erythropoietin (0.1 1 U/mI. p < 0.05) subsided after nephrectomy and again increased with developing lung metastasis (0.1 U/mI, p < 0.02). Erythropolet...
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ژورنال
عنوان ژورنال: Japanese journal of leprosy
سال: 1979
ISSN: 0386-3980,2185-1360
DOI: 10.5025/hansen1977.48.37